• A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016 

      Mikkilä, Saija; Johansson, Jonas; Nordström, Anna Hava; Nordström, Peter; Emaus, Nina; Handegård, Bjørn Helge; Morseth, Bente; Welde, Boye (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-26)
      Aims<p> The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32–86 years old women and men.<p> <p>Methods <p>Data were retrieved from the 2001, 2007–2008, and 2015–2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical ...
    • A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001-2016 

      Mikkilä, Saija; Johansson, Jonas; Nordström, Anna Hava; Nordström, Peter; Emaus, Nina; Handegård, Bjørn Helge; Morseth, Bente; Welde, Boye (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-26)
      Aims<p> <p>The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32–86 years old women and men.<p> <p>Methods <p>Data were retrieved from the 2001, 2007–2008, and 2015–2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical activity ...
    • Adiposity Without Obesity: Associations with Osteoporosis, Sarcopenia, and Falls in the Healthy Ageing Initiative Cohort Study 

      Scott, David; Johansson, Jonas; Ebeling, Peter R.; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-23)
      Objective - Obesity is commonly defined by BMI rather than adiposity, which may have differential effects on musculoskeletal health. Musculoskeletal outcomes were compared in older adults with normal adiposity and normal BMI (NA‐NBMI), those with high adiposity but normal BMI (HA‐NBMI), and those with high adiposity and high BMI (HA‐HBMI).<p> <p>Methods - In 3,411 70‐year‐olds, obesity was defined ...
    • Association Between Risk of COVID-19 Infection in Nonimmune Individuals and COVID-19 Immunity in Their Family Members 

      Nordström, Peter; Ballin, Marcel; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-11)
      Importance - The association between COVID-19 immunity within families and the risk of infection in nonimmune family members is unknown.<p> <p>Objective - To investigate the association between risk of COVID-19 in nonimmune individuals and the number of their family members with known immunity acquired from a previous COVID-19 infection or full vaccination (2 vaccine doses).<p> <p>Design, ...
    • The association of depression with subsequent dementia diagnosis: A Swedish nationwide cohort study from 1964 to 2016 

      Holmquist, Sofie; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-09)
      <p><b>Background</b> Depression is associated with an increased risk of dementia. However, short follow-up times and lack of adjustment for familial factors in previous studies could influence this association. The purpose of the present study was to investigate the association between depression and subsequent dementia, while controlling for familial factors and with a follow-up of over 35 ...
    • Association of dog ownership with accelerometer-measured physical activity and daily steps in 70-year-old individuals: a population-based cross-sectional study 

      Ballin, Marcel; Antonsson, Oskar; Rosenqvist, Viktor; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-21)
      Background: Dog ownership (DO) has been associated with higher levels of self-reported walking and physical activity. However, compared to device-based measures, self-reported measures of physical activity may sufer from bias due to recall and social desirability. They are also incapable of quantifying light-intensity physical activity (LPA) and step volume, both of which may have important health ...
    • Associations of accelerometer-determined physical activity and sedentary behavior with sarcopenia and incident falls over 12 months in community-dwelling Swedish older adults 

      Scott, David; Johansson, Jonas; Gandham, Anoohya; Ebeling, Peter R; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-05)
      <i>Objective</i>: To determine associations of accelerometer-determined time and bouts of sedentary behavior, light physical activity (PA) and moderate-to-vigorous PA (MVPA) with sarcopenia and incident falls over 12 months. <p> <p><i>Methods</i>:A total of 3334 Swedish 70-year-olds were assessed for sarcopenia, as defined by the revised definition of the European Working Group on Sarcopenia in ...
    • Associations of Sarcopenia and Its Components with Bone Structure and Incident Falls in Swedish Older Adults 

      Scott, David; Johansson, Jonas; McMillan, Lachlan; Ebeling, Peter R; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-21)
      The aim of this study was to compare bone structure parameters and likelihood of falls across European Working Group on Sarcopenia in Older People (EWGSOP2) sarcopenia categories. 3334 Swedish 70-year olds had appendicular lean mass (normalized to height; ALMHt), lumbar spine and total hip areal BMD (aBMD) estimated by dual-energy X-ray absorptiometry. Volumetric BMD (vBMD) and structure at the ...
    • Bisphosphonates and mortality: confounding in observational studies 

      Bergman, Jonathan; Nordström, Anna Hava; Hommel, Ami; Kivipelto, Miia; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-31)
      <p><i>Summary - </i>Numerous observational studies suggest that bisphosphonates reduce mortality. This study showed that bisphosphonate use is associated with lower mortality within days of treatment, although the association was not significant until the second week. Such an early association is consistent with confounding, although an early treatment effect cannot be ruled out. <p><i>Introduction ...
    • Cardiovascular Disease and All-Cause Mortality in Male Twins with Discordant Cardiorespiratory Fitness: A Nationwide Cohort Study 

      Ballin, Marcel; Nordström, Anna Hava; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-14)
      Whether genetic and familial factors influence the association between cardiorespiratory fitness (CRF) and cardiovascular disease (CVD) is unknown. Two cohorts were formed based on data from 1,212,295 men aged 18 years who were conscripted for military service in Sweden during 1972–1996. The first comprised 4,260 twin pairs in which the twins in each pair had different CRF (≥1 watt). The second ...
    • Daily step count and incident diabetes in community-dwelling 70-year-olds: a prospective cohort study 

      Ballin, Marcel; Nordström, Peter; Niklasson, Johan; Alamäki, Antti; Condell, Joan; Tedesco, Salvatore; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-30)
      <p>Background</i> - Older adults with diabetes take fewer steps per day than those without diabetes. The purpose of the present study was to investigate the association of daily step count with incident diabetes in community-dwelling 70-year-olds.<p> <p><i>Methods</i> - This prospective cohort study included N = 3055 community-dwelling 70-year-olds (52% women) who participated in a health examination ...
    • Daily steps and all-cause mortality: a meta-analysis of 15 international cohorts 

      Paluch, Amanda E; Bajpai, Shivangi; Bassett, David R; Carnethon, Mercedes R; Ekelund, Ulf; Evenson, Kelly R; Galuska, Deborah A; Jefferis, Barbara J; Kraus, William E; Lee, I-Min; Matthews, Charles E; Omura, John D; Patel, Alpa V; Pieper, Carl F; Rees-Punia, Erika; Dallmeier, Dhayana; Klenk, Jochen; Whincup, Peter H; Dooley, Erin E; Pettee Gabriel, Kelley; Palta, Priya; Pompeii, Lisa A; Chernofsky, Ariel; Larson, Martin G; Vasan, Ramachandran S; Spartano, Nicole; Ballin, Marcel; Nordström, Peter; Nordström, Anna Hava; Anderssen, Sigmund Alfred; Hansen, Bjørge Hermann; Cochrane, Jennifer A; Dwyer, Terence; Wang, Jing; Ferrucci, Luigi; Liu, Fangyu; Schrack, Jennifer; Urbanek, Jacek; Saint-Maurice, Pedro F; Yamamoto, Naofumi; Yoshitake, Yutaka; Newton, Robert L; Yang, Shengping; Shiroma, Eric J; Fulton, Janet E (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-22)
      Background Although 10000 steps per day is widely promoted to have health benefits, there is little evidence to support this recommendation. We aimed to determine the association between number of steps per day and stepping rate with all-cause mortality.<p> <p>Methods In this meta-analysis, we identified studies investigating the effect of daily step count on all-cause mortality in adults (aged ...
    • Digital exercise interventions for improving measures of central obesity: a systematic review 

      Ballin, Marcel; Hult, Andreas; Björk, Sabine; Dinsmore, John; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-14)
      <i>Objectives</i> - We aimed to systematically review the potential benefits of digital exercise interventions for improving measures of central obesity including visceral adipose tissue (VAT) and anthropometric surrogates for VAT in overweight or centrally obese adults aged 18 or over.<p> <p><i>Methods</i> - A systematic literature search was conducted in three databases up until March 2020 ...
    • Effect of berry polyphenols on glucose metabolism: A systematic review and meta-analysis of randomized controlled trials 

      Rambaran, Theresa F.; Bergman, Jonathan; Nordström, Peter; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-26)
      The effect of berry polyphenols on glucose metabolism has been evaluated in several studies; however, the results are conflicting. A systematic review and meta-analysis was therefore conducted to evaluate the effect of berry polyphenol consumption on glucose metabolism in adults with impaired glucose tolerance or insulin resistance. PubMed/MEDLINE, Cochrane Central Register of Controlled Trials, ...
    • Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden 

      Nordström, Peter; Ballin, Marcel; Nordström, Anna (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      <p><b> Background:</b> The effect of a fourth dose of COVID-19 vaccine on the risk of death in the oldest and frailest individuals is unknown. <p><b> Methods</b> Two matched cohorts were formed using Swedish nationwide registers. In the first, residents of long-term care facilities (LTCFs) given a fourth dose of an mRNA vaccine from 1 January 2022 onwards were matched 1:1 on birth year and ...
    • Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden. 

      Nordström, Peter; Ballin, Marcel; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-03)
      Background - The effect of a fourth dose of COVID-19 vaccine on the risk of death in the oldest and frailest individuals is unknown.<p> <p>Methods - Two matched cohorts were formed using Swedish nationwide registers. In the first, residents of long-term care facilities (LTCFs) given a fourth dose of an mRNA vaccine from 1 January 2022 onwards were matched 1:1 on birth year and county of residence ...
    • Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study 

      Nordström, Peter; Ballin, Marcel; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-18)
      Background - The effectiveness of heterologous prime-boost Coronavirus disease 2019 (Covid-19) vaccination is currently unknown.<p> <p>Methods - From individuals vaccinated with two doses against Covid-19 in Sweden until July 5, 2021 (N=3,445,061), we formed a study cohort including 94,569 individuals that had received heterologous ChAdOx1 nCoV-19 / BNT162b2 prime-boost vaccination, 16,402 ...
    • Effects of interval training on quality of life and cardiometabolic risk markers in older adults: a randomized controlled trial 

      Ballin, Marcel; Lundberg, Emmy; Sörlén, Niklas; Nordström, Peter; Hult, Andreas; Nordström, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-04)
      <i>Purpose</i>: To explore the effects of 10 weeks of progressive vigorous interval training as a single intervention on health-related quality of life (HRQoL) and cardiometabolic risk markers in centrally obese 70-year-old individuals.<p><p> <i>Participants and methods</i>: A randomized controlled trial (ClinicalTrials.gov registration no. NCT03450655) including seventy-seven community-dwelling ...
    • Effects of Resistance Training on Functional Strength and Muscle Mass in 70-Year-Old Individuals With Pre-sarcopenia: A Randomized Controlled Trial 

      Vikberg, Sanna; Sorlen, Niklas; Branden, Lisa; Johansson, Jonas; Nordström, Anna Hava; Hult, Andreas; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      Objective: Sarcopenia has been defined as age-related loss of muscle mass and function. The aim of this randomized controlled trial was to examine the effects of a 10-week instructor-led resistance training program on functional strength and body composition in men and women aged 70 years with presarcopenia. Design, Setting, and Participants: Participants were randomized to either 10 weeks of a ...
    • Effects of Resistance Training on Functional Strength and Muscle Mass in 70-Year-Old Individuals With Pre-sarcopenia: A Randomized Controlled Trial. 

      Vikberg, Sanna; Sörlén, Niklas; Brandén, Lisa; Johansson, Jonas; Nordström, Anna; Hult, Andreas; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      <i>Objective</i> - Sarcopenia has been defined as age-related loss of muscle mass and function. The aim of this randomized controlled trial was to examine the effects of a 10-week instructor-led resistance training program on functional strength and body composition in men and women aged 70 years with pre-sarcopenia.<p> <p><i>Design, Setting, and Participants</i> - Participants were randomized ...